The injuries can affect the skin, but scientists try to accelerate the healing process with a new device: a mobile header bioprinter that can help treat injured patients.
Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) have recently developed a cellular bioimpulsion system for the skin, which allows printing the skin in two layers directly into a wound. The team, who posted their conclusions on Scientific reports On February 12, he discovered that this type of treatment, which would use the cells of a patient to "print" the skin and accelerate the healing process, could be useful for hospitals in the future.
Students in @EastCarolina School of Engineering and Technology @ECUCET Got a front row seat a # 3D #bioprinter demonstration, citing the research of director Dr. Section using the same technology. https://t.co/AQ0mHGEGj5 #bioprinting #regenmed pic.twitter.com/lFGh67Weaz
– Wake Forest for Regenerative Medicine Institute (@WFIRMnews) February 19, 2019
"Technology has the potential to eliminate the need for painful skin grafts that cause more disfigurement for patients suffering from major injuries or burns," said the press release of the director of WFIRM, Anthony Atala, M.D. "A mobile bioprinter that can provide on-site management of extensive injuries can help accelerate caregiving and reduce patient costs."
According to the research, chronic, large or non-healing wounds can be expensive for patients and take a long time to heal. However, the mobile header bioprinter can offer a faster and more profitable solution for burning and ulcers using a mixture of large skin cells, including dermal fibroblasts and epidermal keratinocytes and "print" the mixture in the wounds to accelerate skin recovery .
To put this bioprinter to the test, the team printed the skin in preclinical models. First, the main skin cells were mixed in a hydrogel and placed in the bioprinter. Next, integrated image technology, which is a scanning device for the wound, feeds the software information so it tells the print headers where to deliver cells per layer in the wound. The team discovered that this system recurs rapidly and accelerates the formation of skin cells, so the wounds can be repaired in a shorter period of time.
After his experiment, the next team move is to try the bioprinter in a human clinical trial. Although skin grafts are currently used to treat burns and injuries, they can be a challenge due to the low availability of healthy skin. With the bioprinter, healthcare professionals can quickly regenerate skin cells from a patient without the need for grafting or donors in the future.
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