The researchers developed a calculation model for five types of infections based on data from the European European Antimicrobial Resistance Surveillance Network (EARS).
For the year 2015 they calculated the number of people infected in 671,689 and the number of deaths attributable to multidrug resistant bacteria at 33,110.
The impact is "comparable to the cumulative effect of influenza, tuberculosis and the AIDS virus" in the same period, according to the authors.
Most deaths affect children under 12 and those over 65 years of age.
The impact in terms of mortality is higher in Italy and Greece (the first one concentrates more than a third of the deaths), according to the study.
The medical sector constantly warns of the danger of excessive or inappropriate intake of antibiotics, which makes bacteria resistant.
An Australian team highlighted in September the dangerous propagation of resistant bacteria to all existing drugs, Staphylococcus epidermidis, which can cause serious illnesses and even death and are related to Staphylococcus aureus (MRSA) resistant to methicillin.
Of the 671,689 infections caused by a multidrug-resistant bacterium in 2015, about two thirds were hired at the hospital.
The researchers underline the "urgency of considering antibiotic resistance as a vital fact for health" and "the need to devise alternative treatments for patients with other diseases and who are more vulnerable due to the weakening of their immune defenses or their age" .