Monday , May 10 2021

People without an appendix are less likely to suffer from Parkinson's Diario de Cuyo disease




Who went through one appendicitis He knows that it can be very painful. Fortunately, science has just published a novelty that could be the consolation of many: Those who lost that part of the bowel are 20% less likely to develop Parkinson's disease.

The study in Sweden and published in the journal Science Translational Medicine; assure that This small organ, united and open towards the lower end of the large intestine, can contribute to this brain disorder.

"Parkinson's disease is a multisystem disorder," explains Viviane Labrie, lead author of the study and assistant professor at the Van Andel Research Institute in Michigan. "And, therefore, It is possible that they have many sites of origin as far as where Parkinson's disease begins, the gastrointestinal tract is one of them. For other people, you can start in the brain, "he says.

"In the last decade, it became clear that Parkinson's disease is not just a movement disorder." of Labrie. One of the most common non-motor symptoms of this disorder is the problems of the gastrointestinal tract. Therefore, some scientists believe they could start there, the specialist said. He added that the appendix contains a protein, alpha-synuclein, which is known to accumulate or bundle in the brain of Parkinson's patients.

In search of the connection between this disorder and the appendix, Labrie and her colleagues analyzed medical data of 1.6 million people in Sweden. According to the researchers, the results showed that the accomplishment of an appendectectomy is related to a reduction of risk of 19.3% of the development of this disease.

In addition, they examined the records of 849 Parkinson patients and found that An appendectivity was associated with the late onset of the disease in an average of 3.6 years.

"Alpha synuclein is a protein capable of moving from one neuron to another, and it has been shown that you can travel." reveals Labrie. "If it were to enter the brain, it could be sown and spread from there and have neurotoxic effects that could lead to Parkinson's disease," he says.

The study received praise, but also critics of doctors who said that before this news many people would ask to unnecessarily eliminate the appendix.

For his part, the managing director of the Parkinson Foundation and associate professor at the Department of Neuroscience and Physiology at the Faculty of Medicine of the University of New York, James Beck, He supported the results of this new study and said he is "solid."

Parkinson's disease has 60,000 new diagnoses every year, It can be treated but it is not cured. Symptoms include involuntary movements, tremors of the fingers, hands, legs or feet; stiffness; difficulty balance; depression; and gastrointestinal disorders, including constipation. Research has shown that gastrointestinal symptoms can begin up to 20 years before the movement's symptoms.


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