Saturday , April 17 2021

Changes in vascular cells can help early detection

Washington, DC

A new study suggests that atherosclerosis can be detected by signs that contribute to the knowledge of the arterial block, observing how the cells change in their blood vessels, according to the latest discoveries published in the November issue of Natureza Telecom.

The magazine said that long ago it is known that the neurons that contain the blood vessels are multitasking, while their main function is to pump blood into the body, they also participate in injuries, "throw" in the blood vessels. And it can lead to an excessive change in DNA to these hardened cells, leading to the formation of "plaques" in the blood vessels that block the blood flow.

Using modern genome techniques, a multidisciplinary team of researchers in Cambridge and London captured a small number of vascular muscle cells in the blood vessels of mice in the switching process and described its molecular properties. The researchers used an innovative methodology known as the single-cell RNA sequence, The activity of most genomes of the genome is followed by hundreds of individual vascular muscle cells.

The researchers believe that the study could open the way for the detection of "altered" cells in humans, allowing the diagnosis and treatment of atherosclerosis at an early stage in the future.


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