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Fibrosis, liver esteatosis observed in some young adults

Fibrosis, liver esteatosis observed in some young adults

(HealthDay): A considerable proportion of young adults have fibrosis and liver esteatosis, according to a study presented at the International Liver Congress 2019, held from April 10 to 19 in Vienna.

Kushala Abeysekera, M.B.S., from the University of Bristol in the United Kingdom, and her colleagues examined the prevalence of non-alcoholic fatty liver disease among young people in the cohort of Avon's longitudinal study of parents and children. A total of 4,020 participants in the study had fibroscans.

The researchers found that 2.4 percent of the 3,128 individuals whose fibroscopes were available for analysis had evidence of fibrosis and 0.3 percent had fibrosis-equivalent assessments for stage 4 fibrosis. There were correlations with alanine transaminase (ALT), aspartate aminotransferase (AST) and gamma-glutamyl transferase (GGT) with the increase in the score of fibrosis. Of the 3,277 scans that were eligible for the analysis of steatosis, 20.8 percent of the participants had steatosis and 10.1 percent had steatosis in stage 3. More than one observed in women was higher than in men. There were correlations for ALT, AST and GGT increments with the increase in the attenuated controlled parameter score (CAP). There was a positive association for the CAP score with the score of fibrosis.

"We were worried to find that, at only 24 years of age, one in five had steatosis and one in 40 had evidence of fibrosis, based on elastography results, in a group of predominantly asymptomatic, caucasian boys," said Abeysekera, a statement .

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Fibrosis, liver esteatosis observed in some young adults (2019, April 12)
recovered on April 12, 2019

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