The Likud MK Oren Hazan on Monday left a fire after calling Meretz's Law Ministry, Ilan Gilon, "human means."
Hazan later said that he did not refer to Gilon's disability.
The comment occurred during a stormy Knesset debate about legislation that would see government funding for the arts depended on "loyalty."
Gilon had criticized the Minister of Culture Miri Regev, also from the Likud party, from the podium when Hazan came to his defense.
Gilon and Hazan exchanged words before the Likud manager said: "If it were not half human, I would respond."
Gilon replied to Hazan brand "the Golem of Prague".
The Likud MK, who was punished for making fun of a disabled legislator in the past, insisted that his insult was not a jab on the condition of the left-wing legislator.
"My comments refer to their manners. If my statements were interpreted otherwise, accept my apology," said Hazan.
Gilon, who had polio when he was a child, has difficulty walking without help and often uses a wheelchair.
The comment of Hazan attracted the reaction of the opposition MKs, who described the words of the legislator like "revoltantes" and "repulsivos". "If he is not expelled from Likud in the next hour, then this is the true face of the party. This is the way they want to drive Israel. Revolt," wrote Union MK Stav Shaffir on Twitter.
"Let me remind you that this repulsive MK also mocked my friend Karin Elharar for his disability. How disgusting can you be?" Added Union Mionist MK Mickey Rosenthal.
Since choosing Knesset two years ago, Hazan has posted a disabled colleague and has been temporarily expelled from the Knesset twice for several violations. In January, the Knesset Ethics Committee handed Hazan the maximum possible unprecedented punishment in all Knesset years for a series of incidents in which he insulted his compatriots.
In November of 2015, during a night at night, Hazan shouted at the Yesh Atid wheelchair MK Karin Elharar, "Need Issawi to help?". Elharar suffers muscular dystrophy.
Hazan accused him of double illegal vote after she asked Meretz MK Issawi Frej to help her cast his vote in plenary session.
Recently, he told a lawmaker at a Knesset committee meeting that was too ugly to be a prostitute.
Hazan's father, Yehiel Hazan, lost the Knesset's seat after he was trapped, throwing a double vote in full, and then trying to eliminate a voting computer from a Knesset closet to hide the evidence of the act.
The Knesset on Monday night will vote on the first reading of a controversial bill that would allow the Culture Minister to retain funds for cultural organizations "that are working against the principles of the State."
The so-called Law of Culture Loyalty would allow the government to throw away the financing of organizations or events that present any of the five issues: denying that the State of Israel is a Jewish and democratic country; incitement to racism, violence or terror; support for the armed struggle or acts of terror against Israel by an enemy state or by a terrorist group; marking the Independence Day of Israel as a day of mourning; or any act of physical destruction or degradation of the flag or of any state symbol.