Friday, November 9,
Scientists at the American Institute of Dana-Farber for Cancer Research have discovered molecular targets in malignant tumor cells for two types of cancer that can not be treated.
According to MedicalXpress, synovial sarcoma (a rare type of soft tissue cancer commonly detected in young people) and tumors of children under 2 years affect the brain, kidneys and other organs of the body.
The researchers found that the development of synovial sarcoma and pediatric tumors was caused by the reconstitution of chromatin in the compound of ncBAF, which regulates the activity of a series of genes and plays an important role in the packaging of chromatin, which is a chromosome made up of DNA, RNA and proteins.
The researchers also discovered the presence of BRD9 and GLTSCR1 in the compound of ncBAF, which are unique subunits not found in similar compounds.
The inhibition of these units with the help of auxiliary compounds prevents the division and proliferation of malignant cells and, therefore, delays the progression of the disease.
Scientists hope their results help develop new ways to treat synovial sarcoma and pediatric tumors.
Source: Linta. Ru
Source: RT Arabic (Russia Today)