Monday , May 10 2021

Social isolation linked to the highest risk of death – ScienceDaily

A large study by the American Cancer Society unifies social isolation with a higher risk of death for all the combined causes and heart disease for all the breeds studied and with a higher mortality rate for cancer in white men and women. The study, which appears in the American Journal of Epidemiology, says that tackling social isolation is a promise if studies show that interventions are effective, as they could be relatively simple and could influence other risk factors, since social isolation is also related to hypertension, inflammation, inactivity Physics, smoking and other health risks.

Social isolation has been linked to higher mortality in studies that mainly includes white adults, although associations between black adults are unclear. The new prospective cohort study, led by Kassandra Alcaraz, doctor and MPH of the American Cancer Society, evaluated whether social isolation associations with cardiovascular diseases and cancer mortality differentiated between race and sex. The study analyzed the data of 580,182 adults enrolled in the 1982/1983 Cancer-II Prevention Study, which were followed by mortality by 2012.

The researchers measured several standard components of social-marital status isolation, frequency of attendance at religious services and group meetings / group activities and number of close friends / relatives – giving a score of 0 (less isolated) or 1 (the most isolated ) in each of the factors for a total on a 5-point insulation scale. For example, someone who was married, frequently attended religious services, attended club meetings and / or group activities, and had seven or more close friends received an insulation score of 0. Someone with none of them would have an insulating score of 4

They found in general, the breed seems to be a stronger predictor of social isolation than sex; white men and white women were more likely to be in the less isolated category than men and black women. In the complete sample, a positive and statistically significant dose-response relationship was found between social isolation and mortality risk throughout the 30-year follow-up period. However, the associations were significantly stronger in the first 15 years of follow-up.

The social isolation score was positively associated with cardiac mortality (CVD) in all subgroups. Although there was a positive association between social isolation score and cancer mortality among white men and women, there was no association between social isolation score and cancer mortality among black men or black women. Each component of social isolation was associated with mortality due to all causes and CVD, and all but one (who had fewer friends / relatives) were associated with cancer mortality.

"[C]Remote results indicate that a measure of social isolation is a robust predictor of mortality risk among men, women, blacks and whites, "wrote the authors." Compared to the less isolated, the more socially isolated black men and women had more death risk of 2 times greater for any cause, and white men and women had a 60% and 84% higher risk of death, respectful. "

The authors claim that as precision medicine develops, health influences, including social factors, are expected to be more important for clinical care. When addressing social isolation is aligned with this more holistic approach, they write, saying: "The lack of interpersonal connections seems especially damaging."

The authors point to a recent meta-analysis that identified social isolation as an independent risk factor for death on the basis of the well-established risk factors for mortality such as physical inactivity, obesity and lack of access to health. "The persistent challenges when it comes to intervening in modifiable clinical risk factors such as obesity make social-based approaches based on social isolation promise if efficacy can be established," they conclude.

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Materials provided by American Cancer Society. Note: the content can be edited by style and length.

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